In the 55th minute, Daniel Maldini gave the advantage to the locals, after a preparation by M’Bala Nzola. Romelu Lukaku scored in the 83rd minute. The Belgian converted a penalty. M’Bala Nzola then put Spezia back in front. He also did that from 11 meters.
In the first half, Lautaro Martínez missed a penalty for Inter. The Argentinian saw goalkeeper Bartlomiej Dragowski save.
Denzel Dumfries and Stefan de Vrij were absent from the starting line-up at Inter. Dumfries came on in the 66th minute. Jeroen Zoet was the second goalkeeper on the bench at Spezia.
Napoli will face Atalanta on Saturday.